Wikipedia describes Synergy as "the creation of a whole that is greater than the simple sum of its parts."
And that's what takes place with careful assembly of your audio system. One of the beauties of our passion to build great music systems is the mixing and matching of equipment.
Just think of it. While you might have much the same equipment as I do, or your friend does, your music system is absolutely unique. You have a different room at a minimum. Your choices of seating position, interconnecting cables, the furniture you place in your room to hold the system, even the very air you breathe is most likely different than that that I breathe; and air density determines much in the way your music sounds.
Never be afraid to experiment, to mix and match, to do what no one else has done. You already are, by default.